Article
Acute stroke in relation to homocysteine and methylenetetrahydrofolate reductase gene polymorphisms
31 Mar 2006
Abstract excerpt
AIM: Some methylenetetrahydrofolate reductase (MTHFR) gene mutations cause hyperhomocysteinemia and homocystinuria. These may be important risk factors for cardio and cerebrovascular diseases. We investigated whether the MTHFR C677T and A1298C polymorphisms contribute to hyperhomocysteinemia and increase the risk factor for stroke. METHODS: A total of 203 acute stroke patients and 55 controls were recruited....