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Akt: a key transducer in cancer

30 Sept 2022

Abstract excerpt

Growth factor signaling plays a pivotal role in diverse biological functions, such as cell growth, apoptosis, senescence, and migration and its deregulation has been linked to various human diseases. Akt kinase is a central player transmitting extracellular clues to various cellular compartments, in turn executing these biological processes. Since the discovery of Akt three decades ago, the tremendous progress...

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PMID: 36180910
DOI: 10.1186/s12929-022-00860-9

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