Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The relation between PI3K/AKT signalling pathway and cancer

5 Mar 2019

Abstract excerpt

Phosphatidylinositol 3-kinases (PI3Ks) are crucial coordinators of intracellular signalling in response to the extracellular stimulators. Hyperactivation of PI3K signalling cascades is one among the most ordinary events in human cancers. Focusing on the PI3K pathway remains both a chance and a challenge for cancer therapy. The high recurrence of phosphoinositide 3-kinase (PI3K) pathway adjustments in cancer has...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Lymphocytic Leukemia Research
Share to PI3K/AKT/mTOR signaling in cancer
Share to Protein Kinase Regulation and GTPase Signaling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30849534
DOI: 10.1016/j.gene.2019.02.076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The relation between PI3K/AKT signalling pathway and cancerPMID 30849534Read ↗

PI3K and AKT: Unfaithful Partners in CancerSemantic proximity Read ↗

The PTEN–PI3K Axis in CancerSemantic proximity Read ↗

The PTEN-PI3K Axis in CancerSemantic proximity Read ↗

Current State and Future Challenges for PI3K Inhibitors in Cancer TherapySemantic proximity Read ↗

The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications.Semantic proximity Read ↗

Advances in subunits of PI3K class I in cancer.Semantic proximity Read ↗

The PKB/AKT pathway in cancer.Semantic proximity Read ↗

Targeting PI3K in cancer: mechanisms and advances in clinical trialsSemantic proximity Read ↗

AKT in cancer: new molecular insights and advances in drug developmentSemantic proximity Read ↗

PI3K-Akt pathway: Its functions and alterations in human cancerSemantic proximity Read ↗

Oncogenic kinase signalling.Semantic proximity Read ↗

Research progress on the PI3K/AKT signaling pathway in gynecological cancer (Review)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.