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AKT: A Central Node in Complex Signaling Cascades

30 May 2025

Abstract excerpt

Akt (v-akt murine thymoma virus oncogene homologue) is a well-known serine-threonine kinase that functions as a central node in various important signal cascades involved in cellular maintenance. Akt has also been implicated in oncogenic malignancies as evidenced by protein overexpression, activation and somatic aberration of components in the phosphoinositide-3 kinase-Akt pathway. As such, Akt is a potential...

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PMID: 40613282
DOI: 10.31083/fbl26414

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