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Article

Cross-GWAS coherence test at the gene and pathway level.

PLoS computational biology - 1 Sept 2022

Krefl Daniel, Bergmann Sven

Abstract excerpt

Proximal genetic variants are frequently correlated, implying that the corresponding effect sizes detected by genome-wide association studies (GWAS) are also not independent. Methods already exist to account for this when aggregating effects from a single GWAS across genes or pathways. Here we present a rigorous yet fast method for detecting genes with coherent association signals for two traits, facilitating...

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Identifiers

PMID: 36156592
DOI: 10.1371/journal.pcbi.1010517
PMCID: PMC9536597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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