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Article

A novel and cost-efficient allele-specific PCR method for multiple SNP genotyping in a single run.

Analytica chimica acta - 9 Oct 2022

He Qidi, Hu Ou, Chen Meng, Liang Zhixian, Liang Lushan, Chen Zuanguang

Abstract excerpt

Cost-effective methods for DNA genotyping were needed because single nucleotide polymorphisms (SNPs) were essential biomarkers associated with many diseases. Allele-specific PCR (AS-PCR) has the advantages of mature instruments and high sensitivity. But conventional AS-PCR needs to multiply the number of reactions or primers for multiple targets, which complicates the operation and increases the cost. Herein, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36156224
DOI: 10.1016/j.aca.2022.340366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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