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Article

Somatic Mutations and Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2022

Downey Jocelyn, Lam Jacqueline C K, Li Victor O K, Gozes Illana

Abstract excerpt

Alzheimer's disease (AD) represents a global health challenge, with an estimated 55 million people suffering from the non-curable disease across the world. While amyloid-β plaques and tau neurofibrillary tangles in the brain define AD proteinopathy, it has become evident that diverse coding and non-coding regions of the genome may significantly contribute to AD neurodegeneration. The diversity of factors...

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Identifiers

PMID: 36155518
DOI: 10.3233/JAD-220643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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