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Predicting disease-related genes using integrated biomedical networks.

BMC genomics - 25 Jan 2017

Peng Jiajie, Bai Kun, Shang Xuequn, Wang Guohua, Xue Hansheng, Jin Shuilin, Cheng Liang, Wang Yadong, Chen Jin

Abstract excerpt

BACKGROUND: Identifying the genes associated to human diseases is crucial for disease diagnosis and drug design. Computational approaches, esp. the network-based approaches, have been recently developed to identify disease-related genes effectively from the existing biomedical networks. Meanwhile, the advance in biotechnology enables researchers to produce multi-omics data, enriching our understanding on human...

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PMID: 28198675
DOI: 10.1186/s12864-016-3263-4
PMCID: PMC5310285

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