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Article

Large G3BP-induced granules trigger eIF2α phosphorylation.

Molecular biology of the cell - 1 Sept 2012

Reineke Lucas C, Dougherty Jon D, Pierre Philippe, Lloyd Richard E

Abstract excerpt

Stress granules are large messenger ribonucleoprotein (mRNP) aggregates composed of translation initiation factors and mRNAs that appear when the cell encounters various stressors. Current dogma indicates that stress granules function as inert storage depots for translationally silenced mRNPs until the cell signals for renewed translation and stress granule disassembly. We used RasGAP SH3-binding protein (G3BP)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22833567
DOI: 10.1091/mbc.E12-05-0385
PMCID: PMC3442399

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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