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Insights into the Pharmacogenetics of Tacrolimus Pharmacokinetics and Pharmacodynamics

23 Aug 2022

Abstract excerpt

The influence of pharmacogenetics in tacrolimus pharmacokinetics and pharmacodynamics needs further investigation, considering its potential in assisting clinicians to predict the optimal starting dosage and the need for a personalized adjustment of the dose, as well as to identify patients at a high risk of rejection, drug-related adverse effects, or poor outcomes. In the past decade, new pharmacokinetic...

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PMID: 36145503
DOI: 10.3390/pharmaceutics14091755

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