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MicroRNA-122 Regulation of HCV Infections: Insights from Studies of miR-122-Independent Replication

2 Sept 2022

Abstract excerpt

Despite the advancement in antiviral therapy, Hepatitis C remains a global health challenge and one of the leading causes of hepatitis related deaths worldwide. Hepatitis C virus, the causative agent, is a positive strand RNA virus that requires a liver specific microRNA called miR-122 for its replication. Unconventional to the canonical role of miRNAs in translation suppression by binding to 3'Untranslated...

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PMID: 36145436
DOI: 10.3390/pathogens11091005

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