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Gene Expression and Chondrogenic Potential of Cartilage Cells: Osteoarthritis Grade Differences

13 Sept 2022

Abstract excerpt

Recent data suggest that cells isolated from osteoarthritic (OA) cartilage express mesenchymal progenitor cell (MPC) markers that have the capacity to form hyaline-like cartilage tissue. Whether or not these cells are influenced by the severity of OA remains unexplored. Therefore, we analyzed MPC marker expression and chondrogenetic potential of cells from mild, moderate and severe OA tissue. Human osteoarthritic...

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PMID: 36142513
DOI: 10.3390/ijms231810610

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