Article
Osteoarthritis-derived chondrocytes are a potential source of multipotent progenitor cells for cartilage tissue engineering.
Biochemical and biophysical research communications - 21 Oct 2016
Oda Tomoyuki, Sakai Tadahiro, Hiraiwa Hideki, Hamada Takashi, Ono Yohei, Nakashima Motoshige, Ishizuka Shinya, Matsukawa Tetsuya, Yamashita Satoshi, Tsuchiya Saho, Ishiguro Naoki
Abstract excerpt
The natural healing capacity of damaged articular cartilage is poor, rendering joint surface injuries a prime target for regenerative medicine. While autologous chondrocyte or mesenchymal stem cell (MSC) implantation can be applied to repair cartilage defects in young patients, no appropriate long-lasting treatment alternative is available for elderly patients with osteoarthritis (OA). Multipotent progenitor...
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