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Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritis

5 Jun 2009

Abstract excerpt

INTRODUCTION: Recent findings suggest that articular cartilage contains mesenchymal progenitor cells. The aim of this study was to examine the distribution of stem cell markers (Notch-1, Stro-1 and VCAM-1) and of molecules that modulate progenitor differentiation (Notch-1 and Sox9) in normal adult human articular cartilage and in osteoarthritis (OA) cartilage. METHODS: Expression of the markers was analyzed by...

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PMID: 19500336
DOI: 10.1186/ar2719

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