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Article

Hip Osteoarthritis and the Risk of Lacunar Stroke: A Two-Sample Mendelian Randomization Study.

Genes - 3 Sept 2022

Shen Yi, Li Fuju, Cao Lina, Wang Yunyun, Xiao Jing, Zhou Xiaoyi, Tian Tian

Abstract excerpt

Whether hip osteoarthritis (OA) could increase the risk of lacunar stroke (LS) is not well understood. This two-sample Mendelian randomization (MR) study aimed to investigate in depth the effect of genetically predicted hip OA on LS risk. Hip OA-related instrumental variables (IVs) were selected from a genome-wide association study (GWAS) of 393,873 individuals. The summary data of LS were obtained from a GWAS...

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Identifiers

PMID: 36140752
DOI: 10.3390/genes13091584
PMCID: PMC9498627

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