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The whole-cell pertussis vaccine imposes a broad effector B cell response in mouse heterologous prime-boost settings

22 Sept 2022

Abstract excerpt

ÍSince the introduction of new generation pertussis vaccines, resurgence of pertussis has been observed in many developed countries. Former whole-cell pertussis (wP) vaccines are able to protect against disease and transmission but have been replaced in several industrialized countries because of their reactogenicity and adverse effects. Current acellular pertussis (aP) vaccines, made of purified proteins of...

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PMID: 36136586
DOI: 10.1172/jci.insight.157034

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