Article
Different T cell memory in preadolescents after whole-cell or acellular pertussis vaccination.
Vaccine - 17 Dec 2013
Smits Kaatje, Pottier Gaelle, Smet Julie, Dirix Violette, Vermeulen Françoise, De Schutter Iris, Carollo Maria, Locht Camille, Ausiello Clara Maria, Mascart Françoise
Abstract excerpt
To better understand vaccine-induced protection and its potential failure in light of recent whooping cough resurgence, we evaluated quantity as well as quality of memory T cell responses in B. pertussis-vaccinated preadolescent children. Using a technique based on flow cytometry to detect proliferation, cytokine production and phenotype of antigen-specific cells, we evaluated residual T cell memory in a cohort...
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