Article

Long-term analysis of pertussis vaccine immunity uncovers a memory B cell response to whole cell pertussis immunization that is absent from acellular immunized mice

2021-10-01

Abstract excerpt

<h4>ABSTRACT</h4> Over two decades ago acellular pertussis vaccines (aP) replaced whole cell pertussis vaccines (wP) in several countries. Since then, a resurgence in pertussis has been observed, which is hypothesized to be linked to waning immunity. To better understand why waning immunity occurs, we developed a long-term outbred CD1 mouse model to conduct the longest murine pertussis vaccine studies to date, sp...

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Literature Corpus work: 6e28962b-8d56-5dfc-bbef-14f126ecb443
DOI: 10.1101/2021.10.01.462695

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Long-term analysis of pertussis vaccine immunity uncovers a memory B cell response to whole cell pertussis immunization that is absent from acellular immunized miceDOI 10.1101/2021.10.01.462695Read

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