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Article

Systemic BCG immunization induces persistent lung mucosal multifunctional CD4 T(EM) cells which expand following virulent mycobacterial challenge.

PloS one - 1 Jan 2011

Kaveh Daryan A, Bachy Véronique S, Hewinson R Glyn, Hogarth Philip J

Abstract excerpt

To more closely understand the mechanisms of how BCG vaccination confers immunity would help to rationally design improved tuberculosis vaccines that are urgently required. Given the established central role of CD4 T cells in BCG induced immunity, we sought to characterise the generation of memor...

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Identifiers

PMID: 21720558
DOI: 10.1371/journal.pone.0021566
PMCID: PMC3123368

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21720558-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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