Article
Genetically predicted blood pressure, antihypertensive drugs and risk of heart failure: a Mendelian randomization study.
Journal of hypertension - 1 Jan 2023
Lian Jiao, Shi Xuezhong, Jia Xiaocan, Fan Jingwen, Wang Yuping, Zhao Yang, Yang Yongli
Abstract excerpt
BACKGROUND: Elevated blood pressure (BP) was associated with higher risk of heart failure, but the relationship between BP-lowering via antihypertensive drugs and diminution of heart failure was inconclusive. This study aimed to estimate the causal association of BP with heart failure, and explore the effects of BP-lowering through different antihypertensive drug classes on heart failure risk using Mendelian...
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