Article
Using Mendelian randomization study to assess the renal effects of antihypertensive drugs
26 Mar 2021
Abstract excerpt
BACKGROUND: Angiotensin-converting enzyme (ACE) inhibitors and/or in combination with calcium channel blockers (CCBs) are generally recommended as the first-line antihypertensive therapy for people with hypertension and kidney dysfunction. Evidence from large randomized controlled trials comprehensively comparing renal effects of different classes of antihypertensive drugs is lacking. METHODS: We used a Mendelian...