Article
Knee osteoarthritis phenotypes based on synovial fluid immune cells correlate with clinical outcome trajectories.
Osteoarthritis and cartilage - 1 Dec 2022
Trajerova M, Kriegova E, Mikulkova Z, Savara J, Kudelka M, Gallo J
Abstract excerpt
BACKGROUND: Knee osteoarthritis (KOA) is a highly heterogeneous disease encompassing a wide range of clinical phenotypes. Phenotypes based on immune cells and protein pattern in synovial fluid (SF) and their relationship to clinical trajectories have not been described. OBJECTIVE: To assess phenotypes based on immune cells and protein pattern of SF in KOA. DESIGN: SF-derived immune cells were investigated in 119...
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