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Serum Sclerostin and Its Association with Bone Turnover Marker in Metabolic Bone Diseases

10 Sept 2022

Abstract excerpt

Sclerostin is a secreted inhibitor of Wnt/β-catenin signaling that is mainly produced by osteocytes and is an important regulator of bone remodeling. Some studies have evaluated serum sclerostin levels in metabolic bone diseases, but the results have been contradictory. The profile of serum sclerostin levels in patients with osteogenesis imperfecta (OI), X-linked hypophosphatemia (XLH), and Paget’s disease of...

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PMID: 36124027
DOI: 10.1155/2022/7902046

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