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The Role of Sclerostin in Bone Diseases

2 Feb 2022

Abstract excerpt

Sclerostin has been identified as an important regulator of bone homeostasis through inhibition of the canonical Wnt-signaling pathway, and it is involved in the pathogenesis of many different skeletal diseases. Many studies have been published in the last few years regarding sclerostin's origin, regulation, and mechanism of action. The ongoing research emphasizes the potential therapeutic implications of...

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PMID: 35160258
DOI: 10.3390/jcm11030806

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