Article
Association between arterial hypertension and liver outcomes using polygenic risk scores: a population-based study.
Scientific reports - 16 Sept 2022
Åberg Fredrik, Kantojärvi Katri, Männistö Ville, But Anna, Salomaa Veikko, Niiranen Teemu, Färkkilä Martti, Luukkonen Panu, Männistö Satu, Lundqvist Annamari, Perola Markus, Jula Antti
Abstract excerpt
Arterial hypertension (HTA) is associated with liver disease, but causality remains unclear. We investigated whether genetic predisposition to HTA is associated with liver disease in the population, and if antihypertensive medication modifies this association. Participants of the Finnish health-examination surveys, FINRISK 1992-2012 and Health 2000 (n = 33,770), were linked with national electronic healthcare...
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