Article
Genetic risk, adherence to healthy lifestyle behaviors, and risk of cholelithiasis: A population-based cohort study.
Preventive medicine - 1 May 2024
Mi Ningning, Liang Zixin, Yang Man, Zhao Jinyu, Tian Liang, Huang Chongfei, Xie Peng, Wu Siqing, He Qiangsheng, Sun Yuxuan, Lin Yanyan, Yue Ping, Xia Bin, Yuan Jinqiu, Meng Wenbo
Abstract excerpt
OBJECTIVE: Genetic and lifestyles contribute to cholelithiasis, but the impact of adhering to healthy lifestyle on cholelithiasis risk remains uncertain. We aimed to assess combined lifestyle factors and a polygenic risk score on incident cholelithiasis. METHODS: We utilized cholelithiasis genome-wide association study (GWAS) data from FinnGen study, constructing varied polygenic risk score (PRS), and applied...
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