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Imaging sensitive and drug-resistant bacterial infection with [11C]-trimethoprim

14 Sept 2022

Abstract excerpt

BACKGROUNDSeveral molecular imaging strategies can identify bacterial infections in humans. PET affords the potential for sensitive infection detection deep within the body. Among PET-based approaches, antibiotic-based radiotracers, which often target key bacterial-specific enzymes, have considerable promise. One question for antibiotic radiotracers is whether antimicrobial resistance (AMR) reduces specific...

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PMID: 36106638
DOI: 10.1172/jci156679

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