Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative PET Reporter Gene Imaging with [11C]Trimethoprim

1 Jan 2017

Abstract excerpt

There is a need for improved methods to image genetically engineered cells, including immune cells used for cell-based therapy. Given the genetic manipulation inherent to gene therapy, the use of a reporter protein is a logical solution and positron emission tomography (PET) can provide the desired sensitivity and spatial localization. We developed a broadly applicable PET imaging strategy based on the small...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Glioma Diagnosis and Treatment
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28129108
DOI: 10.1016/j.ymthe.2016.10.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative PET Reporter Gene Imaging with [11C]TrimethoprimPMID 28129108Read ↗

Imaging sensitive and drug-resistant bacterial infection with [11C]-trimethoprimSemantic proximity Read ↗

Imaging Sensitive and Drug-Resistant Bacterial Infection with [ <sup>11</sup> C]-TMP: <i>In Vitro</i> and First-in-Human EvaluationSemantic proximity Read ↗

Positron Emission Tomography Reporter Genes and Reporter Probes: Gene and Cell Therapy ApplicationsSemantic proximity Read ↗

Genetically targeted reporter imaging of deep neuronal network in the mammalian brainSemantic proximity Read ↗

A genetically encoded protein tag for control and quantitative imaging of CAR T cell therapySemantic proximity Read ↗

Radiochemical Approaches to Imaging Bacterial Infections: Intracellular versus Extracellular TargetsSemantic proximity Read ↗

Molecular imaging of gene expression and protein function in vivo with PET and SPECTSemantic proximity Read ↗

Imaging bacterial infections with radiolabeled 1-(2′-deoxy-2′-fluoro-β-D-arabinofuranosyl)-5-iodouracilSemantic proximity Read ↗

Imaging Transgene Expression with Radionuclide Imaging TechnologiesSemantic proximity Read ↗

PET imaging of herpes simplex virus type 1 thymidine kinase (HSV1-tk) or mutant HSV1-sr39tk reporter gene expression in mice and humans using [18F]FHBG.Semantic proximity Read ↗

Covalent 18F-Radiotracers for SNAPTag: a New Toolbox for Reporter Gene ImagingSemantic proximity Read ↗

Antigen-dependent inducible T cell reporter system for PET imaging of breast cancer and glioblastomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.