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Article

Secondary‐type mutations do not impact prognosis in acute myelogenous leukemia AML with mutated NPM1

15 Sept 2022

Abstract excerpt

The 2022 update to the World Health Organization (WHO) classification1 revised the category of acute myeloid leukemia (AML) with myelodysplasia-related changes (AML-MRC) to “AML, myelodysplasia-related,” which now includes cases harboring “secondary-type” mutations (STM) in SRSF2, SF3B1, U2AF1, ZRSR2, ASXL1, EZH2, BCOR, and/or STAG2. Furthermore, the recent 2022 International Consensus Classification (ICC) of...

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PMID: 36106410
DOI: 10.1002/ajh.26730

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