Article
Triple-negative Thrombocythemia and Subsequent Acute Lymphoblastic Leukemia with Additional Somatic Mutations.
Internal medicine (Tokyo, Japan) - 15 May 2023
Tsuboi Yuri, Sakamoto Tatsuhiro, Makishima Kenichi, Suehara Yasuhito, Hattori Keiichiro, Kurita Naoki, Yokoyama Yasuhisa, Kato Takayasu, Nishikii Hidekazu, Obara Naoshi, Matsumura Fumiaki, Matsuoka Ryota, Chiba Shigeru, Sakata-Yanagimoto Mamiko
Abstract excerpt
Triple-negative essential thrombocythemia (ET) is a condition in which mutations in JAK2, CALR and MPL are all negative. Transformation to acute myeloid leukemia may occur during the course of ET, while B-acute lymphoblastic leukemia B-(ALL) is rare. We experienced a case diagnosed as B-ALL during the course of triple-negative ET. Notably, cytoreduction was required for the excessive increase in blood cells...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.