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Article

[Clinical Characteristic of "triple-negative" Essential Thrombocythaemia Patients and Mutation Analysis by Targeted Sequencing].

Zhongguo shi yan xue ye xue za zhi - 1 Aug 2018

Ju Man-Kai, Fu Rong-Feng, Li Hui-Yuan, Liu Xiao-Fan, Xue Feng, Chen Yun-Fei, Huang Yue-Ting, Zhang Li-Yan, Yang Ren-Chi, Zhang Lei

Abstract excerpt

BACKGROUND: Essential thrombocythemia is a subgroup of myeloproliferative neoplasms. Previous studies identified mutations of JAK2, CALR, and MPL that are closely related with the pathogenesis of myeloproliferative neoplasms. All these mutations contribute to the hyperactivation of JAK2/STAT pathway. However, a small proportion of essential thrombocythemia patients does not display such mutations. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30111420
DOI: 10.7534/j.issn.1009-2137.2018.04.032

Genes

ASXL1
JAK2
MPL
TET2
ADAMTS1
CALR
CUX1
EGFR
FLT3
GATA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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