Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clonal evolution process from essential thrombocythemia to acute myeloid leukemia in the original patient from whom the CALR-mutated Marimo cell line was established.

Nagoya journal of medical science - 1 May 2024

Ushijima Yoko, Ishikawa Yuichi, Nishiyama Takahiro, Kawashima Naomi, Kanamori Takashi, Sanada Masashi, Kiyoi Hitoshi

Abstract excerpt

We previously reported the Marimo cell line, which was established from the bone marrow cells of a patient with essential thrombocythemia (ET) at the last stage after transformation to acute myeloid leukemia (AML). This cell line is widely used for the biological analysis of ET because it harbors CALR mutation. However, genetic processes during disease progression in the original patient were not analyzed. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calreticulin
Share to Clonal Evolution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP Phosphohydrolases

Share to Janus Kinase 2

Share to Leukemia, Myeloid, Acute

Share to Receptors, Thrombopoietin

Share to Thrombocythemia, Essential

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 38962422
DOI: 10.18999/nagjms.86.2.326
PMCID: PMC11219235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clonal evolution process from essential thrombocythemia to acute myeloid leukemia in the original patient from whom the CALR-mutated Marimo cell line was established.PMID 38962422Read ↗

Triple-negative Thrombocythemia and Subsequent Acute Lymphoblastic Leukemia with Additional Somatic Mutations.Semantic proximity Read ↗

CALR-mutated essential thrombocythemia evolving to chronic myeloid leukemia with coexistent CALR mutation and BCR-ABL translocation.Semantic proximity Read ↗

Initiating-clone analysis in patients with acute myeloid leukemia secondary to essential thrombocythemia.Semantic proximity Read ↗

CALR mutational status identifies different disease subtypes of essential thrombocythemia showing distinct expression profiles.Semantic proximity Read ↗

Leukemic evolution of polycythemia vera and essential thrombocythemia: genomic profiles predict time to transformation.Semantic proximity Read ↗

[Analysis of Essential Thrombocythemia to Acute Myeloid Leukemia].Semantic proximity Read ↗

Genomics of clonal evolution in a rare essential thrombocythemia with coexisting Type 2 CALR and MPL S204P mutations.Semantic proximity Read ↗

[Clinical Characteristics and Bone Marrow Histopathology Features in Essential Thrombocythaemia Patients with Different Gene Mutation in China].Semantic proximity Read ↗

Incidence, clinical features, and prognostic impact of CALR exon 9 mutations in essential thrombocythemia and primary myelofibrosis: an experience of a single tertiary hospital in Korea.Semantic proximity Read ↗

The mutant CALR allele burden in essential thrombocythemia at transformation to acute myeloid leukemia.Semantic proximity Read ↗

The clinical and prognostic relevance of driver mutations in 203 Taiwanese patients with primary myelofibrosis.Semantic proximity Read ↗

Frequency of Calreticulin (CALR) Mutation and Its Clinical Prognostic Significance in Essential Thrombocythemia and Primary Myelofibrosis: A Meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.