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Body Mass Index and Polygenic Risk for Alzheimer’s Disease Predict Conversion to Alzheimer’s Disease

21 Apr 2021

Abstract excerpt

Body mass index (BMI) is a risk factor for Alzheimer's disease (AD) although the relationship is complex. Obesity in midlife is associated with increased risk for AD, whereas evidence supports both higher and lower BMI increasing risk for AD in late life. This study examined the influence of individual differences in genetic risk for AD to further clarify the relationship between late-life BMI and conversion to...

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PMID: 33880516
DOI: 10.1093/gerona/glab117

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