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Whole transcriptome sequencing reveals neutrophils’ transcriptional landscape associated with active tuberculosis

18 Aug 2022

Abstract excerpt

Neutrophils have been recognized to play an important role in the pathogenesis of tuberculosis in recent years. Interferon-induced blood transcriptional signatures in ATB are predominantly driven by neutrophils. In this study, we performed global RNA-seq on peripheral blood neutrophils from active tuberculosis patients (ATB, n=15); latent tuberculosis infections (LTBI, n=22); and healthy controls (HC, n=21). The...

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PMID: 36059536
DOI: 10.3389/fimmu.2022.954221

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