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Computational reassessment of RNA-seq data reveals key genes in active tuberculosis

27 Jun 2024

Abstract excerpt

BACKGROUND: Tuberculosis is a serious life-threatening disease among the top global health challenges and rapid and effective diagnostic biomarkers are vital for early diagnosis especially given the increasing prevalence of multidrug resistance. METHODS: Two human whole blood microarray datasets, GSE42826 and GSE42830 were retrieved from publicly available gene expression omnibus (GEO) database. Deregulated genes...

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PMID: 38935691
DOI: 10.1371/journal.pone.0305582

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