Article
STAT3 and PD-L1 are negatively correlated with ATM and have impact on the prognosis of triple-negative breast cancer patients with low ATM expression.
Breast cancer research and treatment - 1 Nov 2022
Song Yuan-Ming, Qian Xiao-Long, Xia Xiao-Qing, Li Ya-Qing, Sun Yuan-Yuan, Jia Yu-Mian, Wang Jin, Xue Hui-Qin, Gao Guang-Shen, Wang Xiao-Zi, Zhang Xin-Min, Guo Xiao-Jing
Abstract excerpt
INTRODUCTION: Triple-negative breast cancer (TNBC) is known for its aggressive behaviors and lacking of effective treatment. Programmed cell death ligand-1 (PD-L1) inhibitor has just been approved for using in the management of advanced TNBC. To accurately screen TNBC sensitive to anti-PD-L1 treatment and to explore the feasibility of the ataxia-telangiectasia mutation protein (ATM) inhibitor combined with PD-L1...
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