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Article

Expression patterns of the <i>ATM</i> gene in mammary tissues and their associations with breast cancer survival

15 Mar 2007

Abstract excerpt

BACKGROUND: The ataxia-telangiectasia mutated (ATM) gene plays a critical role in cell-cycle arrest, apoptosis, and DNA repair. However, to date, no study has directly investigated the association between ATM gene expression and breast cancer survival. METHODS: ATM gene expression levels were evaluated in tumor and adjacent normal tissue from patients diagnosed with primary breast cancer or BBD using quantitative...

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PMID: 17366603
DOI: 10.1002/cncr.22592

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