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Article

Effects of putrescine on the quality and epigenetic modification of mouse oocytes during in vitro maturation

29 Aug 2022

Abstract excerpt

CONTEXT: Low ovarian putrescine levels and decreased peak values following luteinising hormone peaks are related to poor oocyte quantity and quality in ageing women. AIMS: To investigate the effects of putrescine supplementation in in vitro maturation (IVM) medium on oocyte quality and epigenetic modification. METHODS: Germinal vesicle oocytes retrieved from the ovaries of 8-week-old and 9-month-old mice were...

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PMID: 36031717
DOI: 10.1071/rd22064

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