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Effects of n-3 PUFA supplementation on oocyte in vitro maturation in mice with polycystic ovary syndrome

29 Apr 2023

Abstract excerpt

n-3 PUFAs are classic antioxidant that can be used to treat follicular dysplasia and hyperinsulinemia caused by excessive oxidative stress in PCOS women. To investigate the effect of n-3 PUFA supplementation on the oocyte quality of polycystic ovary syndrome (PCOS) mice during in vitro maturation, a PCOS mouse model was established by dehydroepiandrosterone (DHEA). The GV oocytes of the control and PCOS groups...

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PMID: 37120599
DOI: 10.1186/s13048-023-01162-w

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