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Article

Standing Genetic Diversity and Transmission Bottleneck Size Drive Adaptation in Bacteriophage Qβ.

International journal of molecular sciences - 9 Aug 2022

Somovilla Pilar, Rodríguez-Moreno Alicia, Arribas María, Manrubia Susanna, Lázaro Ester

Abstract excerpt

A critical issue to understanding how populations adapt to new selective pressures is the relative contribution of the initial standing genetic diversity versus that generated de novo. RNA viruses are an excellent model to study this question, as they form highly heterogeneous populations whose genetic diversity can be modulated by factors such as the number of generations, the size of population bottlenecks, or...

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Identifiers

PMID: 36012143
DOI: 10.3390/ijms23168876
PMCID: PMC9408265

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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