Article
Increased RNA virus population diversity improves adaptability.
Scientific reports - 25 Mar 2021
Mattenberger Florian, Vila-Nistal Marina, Geller Ron
Abstract excerpt
The replication machinery of most RNA viruses lacks proofreading mechanisms. As a result, RNA virus populations harbor a large amount of genetic diversity that confers them the ability to rapidly adapt to changes in their environment. In this work, we investigate whether further increasing the initial population diversity of a model RNA virus can improve adaptation to a single selection pressure, thermal...
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