Article
RNA virus population diversity: implications for inter-species transmission.
Current opinion in virology - 1 Dec 2011
Bordería Antonio V, Stapleford Kenneth A, Vignuzzi Marco
Abstract excerpt
RNA viruses are notorious for rapidly generating genetically diverse populations during a single replication cycle, and the implications of this mutant population, often referred to as quasispecies, can be vast. Previous studies have linked RNA virus genetic variability to changes in viral pathogenesis, the ability to adapt to a host during infection, and to the acquisition of mechanisms required to switch hosts...
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