Contribution of silent mutations to thermal adaptation of RNA bacteriophage Qβ.

Abstract excerpt

UNLABELLED: Changes in protein function and other biological properties, such as RNA structure, are crucial for adaptation of organisms to novel or inhibitory environments. To investigate how mutations that do not alter amino acid sequence may be positively selected, we performed a thermal adaptation experiment using the single-stranded RNA bacteriophage Qβ in which the culture temperature was increased from...

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