Molecular mechanisms and genetic features of cholangiocarcinoma: implications for targeted therapeutic strategies

Abstract excerpt

Cholangiocarcinoma (CCA) is a biologically diverse and highly aggressive cancer that arises from the biliary epithelium. It is typically divided into intrahepatic, perihilar, and distal types, each with distinct clinical behavior, genetic alterations, and therapeutic responses. Worldwide, the global incidence of CCA has risen steadily, accounting for nearly 15% of liver cancers and ∼3% of all gastrointestinal...

Topics

Join the communities discussing this publication.

• Cancer Mechanisms and Therapy
• Cholangiocarcinoma and Gallbladder Cancer Studies
• Peptidase Inhibition and Analysis