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Article

Atypical Alzheimer's disease phenotypes with normal or borderline PET biomarker profiles.

Journal of neurology - 1 Dec 2022

Singh Neha Atulkumar, Graff-Radford Jonathan, Machulda Mary M, Schwarz Christopher G, Baker Matthew C, Rademakers Rosa, Ertekin-Taner Nilufer, Lowe Val J, Josephs Keith A, Whitwell Jennifer L

Abstract excerpt

Posterior cortical atrophy (PCA) and logopenic progressive aphasia (LPA) are clinical syndromes that commonly have underlying Alzheimer's disease (AD), although non-AD pathologies have also been reported. PET imaging allows for identification of beta-amyloid (Aβ) and tau in AD, so we aimed to assess these in a large cohort to identify patients that do not have evidence for biomarker-defined AD. Eight-one...

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Identifiers

PMID: 36001141
DOI: 10.1007/s00415-022-11330-5
PMCID: PMC9707302

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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