Article
Role of ACE2 and TMPRSS2 polymorphisms on COVID-19 outcome and disease severity in adult patients: A prospective cohort study in a tertiary hospital, Indonesia.
Narra J - 1 Aug 2024
Yunita Rina, Wahyuni Arlinda S, Sinaga Bintang Ym, Yamamoto Zulham, Soebandrio Amin, Kusumawati R Lia, Sembiring Rosita J, Pandia Pandiaman
Abstract excerpt
Coronavirus disease 2019 (COVID-19) has led to a significant number of infections and deaths worldwide, yet its pathogenesis and severity remain incompletely understood. Angiotensin-converting enzyme 2 (ACE2) and transmembrane protease, serine 2 (TMPRSS2), play crucial roles as receptors and molecules responsible for the virus's entry into host cells, initiating the infection process. Their polymorphisms have...
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