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Article

Association of JAK/STAT genetic variants with cutaneous melanoma

2 Aug 2022

Abstract excerpt

Background The Janus-activated kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway regulates cutaneous melanoma (CM) development and progression. The JAK1, JAK2, and STAT3 proteins are encoded by polymorphic genes. This study aimed to verify whether single-nucleotide variants (SNVs) in JAK1 (c.1648+1272G>A, c.991-27C>T), JAK2 (c.-1132G>T, c.-139G>A), and STAT3 (c.*1671T>C,...

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Share to Cutaneous Melanoma Detection and Management
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Identifiers

PMID: 35982955
DOI: 10.3389/fonc.2022.943483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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