Article
Polymorphisms in JAK/STAT signaling pathway genes and risk of non-Hodgkin lymphoma.
Leukemia research - 1 Sept 2013
Chen Yingtai, Lan Qing, Zheng Tongzhang, Zhao Nan, Holford Theodore R, Lerro Catherine, Dai Min, Huang Huang, Liang Jiaxin, Ma Shuangge, Leaderer Brian, Boyle Peter, Chanock Stephen, Rothman Nathaniel, Zhang Yawei
Abstract excerpt
Impaired function of Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway genes leads to immunodeficiency and various hematopoietic disorders. We evaluated the association between genetic polymorphisms (SNPs) in 12 JAK/STAT pathway genes (JAK3, STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, STAT6, SCOS1, SCOS2, SCOS3, and SCOS4) and NHL risk in a population-based case-control...
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