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Article

Impact of AKT1 polymorphism on DNA damage, BTG2 expression, and risk of colorectal cancer development.

Radiology and oncology - 14 Aug 2022

Zubair Hina, Khan Zahid, Imran Muhammad

Abstract excerpt

BACKGROUND: AKT, also called protein kinase B, is a serine-threonine kinase that functions as a mediator of PI3K-Akt-mTOR signaling pathway and plays an important role in an array of cellular processes. Many single nucleotide polymorphisms (SNP) in AKT gene have been observed to be associated with various types of cancers. In the current research the association of a functional SNP rs1130233 in AKT, depicting G...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35962953
DOI: 10.2478/raon-2022-0031
PMCID: PMC9400445

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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