Article
Helicobacter pylori infection and DNMT3a polymorphism are associated with the presence of premature coronary artery disease and subclinical atherosclerosis. Data from the GEA Mexican Study.
Microbial pathogenesis - 1 Sept 2022
Vargas-Alarcón Gilberto, Avilés-Jiménez Francisco, Mejía-Sánchez Fernando, Pérez-Hernández Nonanzit, Cardoso-Saldaña Guillermo, Posadas-Sánchez Rosalinda
Abstract excerpt
BACKGROUND: The association between H. pylori infection and coronary artery disease (CAD) is well-known. Alterations in DNA methylation in CAD have been reported, which can be induced by H. pylori through the DNA demethylases (DNMTs). The objective was to analyze the association and interaction of H. pylori infection and DMNT3a gene polymorphisms with premature CAD (pCAD) and subclinical atherosclerosis (SA)....
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